Chinese symbol for walker.

Walker Movie

A movie of sequence walkers moving across a fixed
sequence.

This is a "sequence walker". The row of letters contains only a, c, g and t, and represent a DNA sequence of bases. The letters at each position don't change - watch it carefully to confirm this. The colored part is the "walker" for the Fis protein. It shows how the protein and DNA would react to each other if the protein were at different positions. Letters that go up mean they like being together there, down means the protein and DNA don't like that combination. The sine wave represents the twist of B-form DNA, with major grooves pointing toward the protein being the crest and minor grooves pointing away from the protein being the trough. The heights are measured in bits of information which is the only method that makes the heights additive. Don't be fooled by other methods that won't let you compare different positions on a single universal scale!

For further information about walkers go here.

This technology is available for license. For more information please contact us!

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The movie was made using gifmerge. It used to bomb netscape and hang explorer because the gif images varied in size. When I normalized the images, the problem was solved.

color bar Small icon for Theory of Molecular Machines: physics,
chemistry, biology, molecular biology, evolutionary theory,
genetic engineering, sequence logos, information theory,
electrical engineering, thermodynamics, statistical
mechanics, hypersphere packing, gumball machines, Maxwell's
Daemon, limits of computers


Schneider Lab

origin:    1996 Oct 18
updated: 2011 Aug 24

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