Thermodynamics of Aging

GEORGI P. GLADYSHEV (Academy of Creative Endeavors, Institute of Physico-Chemical Problems of Evolution, Novy Arbat, 36, Moscow, 121205, Russia).

Abstract for 1998 American Association for the Advancement of Science (AAAS) Annual Meeting and Science Innovation Exposition Philadelphia, Pennsylvania Monday, February 16, 1998, 3:00pm-6:00pm Track: Emerging Science: Transforming the Next Generation Session number: 101.0

The findings of macrothermodynamics (supramolecular thermodynamics) of quasi-closed systems and the published data about the variation of the chemical composition of living organisms in ontogeny confirm the thermodynamic tendency of aging processes. According to the thermodynamic theory the specific value of the Gibbs function of the formation of supramolecular structures of the organism tends to a minimum. That tendency explains the variation of the supramolecular and chemical composition and the morphology of tissues during aging. The theory makes it possible to define the principles upon which proper diets and medications can be devised to slow down aging. Such diets and medications are also useful in preventative care and in the treatment of various pathologies and among them those attending old age. The principle of the stability of chemical substance of the supramolecular structures of tissues makes it possible to understand the causes of the practically unlimited evolution of the biological world from the perspective of the Second Law in its classical definition. General references: Gladyshev G.P. Thermodynamic Theory of the Evolution of Living Beings. N.Y.: Nova Sci. Publ. Inc., 1997; J.Biol. Physics 23 (2), 129-131, June 1997;

U.S. Department of Health and Human Services  |  National Institutes of Health  |  National Cancer Institute  |  | 
Policies  |  Viewing Files  |  Accessibility  |  FOIA